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    December 21, 2025
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Pneumococcal Vaccine Study for Older Adults Interested in Receiving an Investigational Pneumococcal Vaccine? Why Is This Study Being Done? We want to learn about the safety and immune system response to an investigational vaccine called PG4. What Is Involved? A screening visit to review medical history, medications, physical exam, and obtain blood A vaccination visit to receive at random 1 of 6 pneumococcal vaccines being studied Attend 4 in-person follow up visits with blood draws Receive a 2nd dose at either 2 months or 6 months after first vaccination E-Diary app to document symptoms Receive $125 for each completed visit Who Is Eligible? Persons are eligible who: Are 65 to less than 85 years of age Have never received a pneumococcal vaccine or received PPSV23 more than 5. years ago Are not immunocompromised Contact If you are interested in participating or have questions: Email DVTUstudies@DM.Duke.edu. Write "Pfizer 1020" in the subject line. Call or leave a message at 919-971-5649. Indicate your first and last names, and the best phone number to reach you. DukeHealth Pro00118817 Pneumococcal Vaccine Study for Older Adults Interested in Receiving an Investigational Pneumococcal Vaccine ? Why Is This Study Being Done ? We want to learn about the safety and immune system response to an investigational vaccine called PG4 . What Is Involved ? A screening visit to review medical history , medications , physical exam , and obtain blood A vaccination visit to receive at random 1 of 6 pneumococcal vaccines being studied Attend 4 in - person follow up visits with blood draws Receive a 2nd dose at either 2 months or 6 months after first vaccination E - Diary app to document symptoms Receive $ 125 for each completed visit Who Is Eligible ? Persons are eligible who : Are 65 to less than 85 years of age Have never received a pneumococcal vaccine or received PPSV23 more than 5 . years ago Are not immunocompromised Contact If you are interested in participating or have questions : Email DVTUstudies@DM.Duke.edu . Write " Pfizer 1020 " in the subject line . Call or leave a message at 919-971-5649 . Indicate your first and last names , and the best phone number to reach you . DukeHealth Pro00118817